Potential new treatment for Alzheimer's disease using a drug already FDA approved for another purpose

An “important breakthrough” in Alzheimer’s disease treatment may soon be forthcoming. Local doctor Gerard Nuovo, MD recently published a study revealing encouraging results using an existing drug and mice.
An estimated seven million people in the US suffer from Alzheimer's disease. Although some treatments are available, they are expensive, may slow the disease down a bit, but offer no cure. Some have potentially negative side effects.
The study is considered “pre-clinical” because drugs must be tested in animals before they can be tested in people. Surprisingly, mouse models of Alzheimer's disease are extensively used in research. They are valuable because the mouse brain has the actual human gene that can cause Alzheimer's disease.
In human Alzheimer's disease, certain proteins called “BCL2 family proteins” concentrate in the damaged neurons. A mouse model of the disease involves giving mice the human gene that causes Alzheimer’s then administering a drug to block the BCL2 protein.
Responding to Trump's Militarism

Tuesday, February 18, 2025, 4:30pm PT, 5:30pm MT, 6:30pm CT, 7:30pm ET
Regional Veterans For Peace hosted Zoom meeting
President’s Day Protest

Monday, February 17, 2025, 12:00 – 8:00 PM
This President’s Day protest is sponsored by the 5050/1 group. Location: Ohio Statehouse.
More information here.
From Doctors Against Genocide: Urgent Support Needed for Senate Resolution Against U.S. Military Intervention & Forced Displacement in Gaza, Restore UNRWA Funding and Protection of Healthcare

As concerned citizens, we urge our elected officials to protect international laws.
1. Support for S.Res. 68, a Senate resolution which says the U.S. should not occupy Gaza and displace its residents.
2. Support for Welch's S.5388 bill asking to restore UNRWA funding. UNRWA is an essential UN program built to support Palestinians in refugee camps as they work for their right to return to the land they were ethnically cleansed from in the Nakba.
3. Demanding full protection for healthcare workers and Institutions everywhere, ensuring they can provide lifesaving care without fear of attack, detention, or persecution.
‘A sad state of affairs:’ Ohio Fairness Act introduced for the 12th time, despite waning bipartisan support for LGBTQ+ civil rights

This article first appeared on the Buckeye Flame.
Ohio Senate Minority Leader and out lesbian Sen. Nickie Antonio (D-Lakewood) has re-introduced the Ohio Fairness Act for the 12th time, despite waning support among Republican lawmakers.
The Fairness Act – which would extend equal civil rights protections to LGBTQ+ Ohioans – was formerly a bipartisan bill.
However, Antonio said the Trump administration’s focus on anti-transgender policy and rhetoric has helped set an increasingly anti-LGBTQ+ precedent at the Ohio Statehouse.
“We should already have equal rights in the state of Ohio, so it’s important to introduce legislation that calls for that,” Antonio said. “People from the LGBTQ+ community should already receive equal treatment under the law – and that means in employment, in housing and when traversing the public sphere.”
Blue states hope their clean energy plans withstand collision with Trump

This article first appeared on the Capital Journal
For states that are pursuing plans to build more wind and solar projects, the federal government has suddenly shifted from a powerful ally to a formidable opponent.
State leaders are still scrambling to make sense of President Donald Trump’s flurry of executive orders, funding freezes, agency directives and verbal threats about clean energy. It’s as if the teammate who had passed them the ball is now trying to block their shot.
50501 Movement: A National Call for Justice, Integrity, and Accountability

The 50501 Movement is a coalition demanding justice, transparency, accountability, and an end to executive overreach. Despite being seen as leaderless, every individual, state, city, grassroots organization, and activist are leaders in this movement. Together, they guide us toward a future based on foundational principles. On February 5th we help mobilize over 20,000 like-minded individuals, activists, and organizations to stand against the harmful impacts of the current administration and Project 2025.
In truth, the 50501 Movement does not refer to an organization—it represents a vision, the American Dream, as we were all once taught to believe it. Each voice of this movement, peacefully united, forms a rallying cry and demand for the "American Dream" that we once all held close to our heart. A dream that we feel has prove
This is not just a movement—it is our modern-day civil rights struggle.
Vegan Lotherio: Ne’s Chinese Food After Kendrick Defuses Nuremberg

I’m contemplating Slutty Vegan should open a North Campus location. I contemplated the lack of vegan options in my immediate neighborhood. Slutty Vegan is a vegan burger place in ATL, NY, TX, and Alabama.
I perused my immediate vegan options within a short walk. I remembered I love Ne’s Chinese Food. During Covid, Ne’s Chinese Food, 2620 N High St, Columbus, OH 43202, built stringed contraptions for no contact payment, and food reception. Ne’s was like San Rio made a cute scene in a Godzilla movie during Covid.
Ne’s veg options offers American Favorites, and Main menus. Ne’s sticks out because of the Eggplant Dishes.
I ordered Fried Potato, Eggplant, Green Peppers and rice. Big round eggplants, with small potatoes and slices of small green peppers are scrumptious. Other main favorites include Eggplant with Brown Sauce, and Home Style Tofu. I haven’t tried the Cumin Green Bean, or Cumin Fried tofu, yet.
While I don’t know the differences between the American, and Main Menu. From the American menu, I order Sichuan Tofu, Sichuan Eggplant, and Tofu Vegetables.
I ate food while watching TV.
Vegan Lotherio: Ne’s Chinese Food After Kendrick Defuses Nuremberg

I’m contemplating Slutty Vegan should open a North Campus location. I contemplated the lack of vegan options in my immediate neighborhood. Slutty Vegan is a vegan burger place in ATL, NY, TX, and Alabama.
I perused my immediate vegan options within a short walk. I remembered I love Ne’s Chinese Food. During Covid, Ne’s Chinese Food, 2620 N High St, Columbus, OH 43202, built stringed contraptions for no contact payment, and food reception. Ne’s was like San Rio made a cute scene in a Godzilla movie during Covid.
Ne’s veg options offers American Favorites, and Main menus. Ne’s sticks out because of the Eggplant Dishes.
I ordered Fried Potato, Eggplant, Green Peppers and rice. Big round eggplants, with small potatoes and slices of small green peppers are scrumptious. Other main favorites include Eggplant with Brown Sauce, and Home Style Tofu. I haven’t tried the Cumin Green Bean, or Cumin Fried tofu, yet.
While I don’t know the differences between the American, and Main Menu. From the American menu, I order Sichuan Tofu, Sichuan Eggplant, and Tofu Vegetables.
I ate food while watching TV.
Video of rally to end war on Black America and defend immigrant families

People in Columbus Ohio gathered on Saturday, February 8 at the Ohio Statehouse to defend immigrant families and end the war on Black America.